Phil Foden, on as a substitute, produced the moment of magic to unlock Atletico with a perfect pass through the legs of Reinildo for De Bruyne to slot past goalkeeper Jan Oblak.

It was the decisive moment in the tightest of games but City manager Pep Guardiola's wild celebration illustrated just how much it means to take a lead, even if slender, to Madrid for the second leg on 13 April.

Foden introduction sparks City

It was clear from the opening moments this was going to be a night for patience from City as Atletico, to no-one's great surprise, strung a bank of five defenders across the pitch and invited Guardiola's side to break them down.

For the first 45 minutes it worked to perfection as the hosts barely laid a glove on the Spanish champions, who protected keeper Oblak with the diligence and desire Simeone demands.

It was actually Atletico who threatened with a couple of breaks early in the second half, but City eventually managed to impose themselves and become more of a threat.

De Bruyne saw a free-kick well saved by Oblak and Aymeric Laporte headed over from a good position following a corner.

But it was the introduction of Foden that finally allowed City to spread some stardust on proceedings.

He showed glorious control and vision to nutmeg Reinildo, allowing De Bruyne to fire low past Oblak to ignite what had been a tense, largely subdued atmosphere inside Etihad Stadium.

City could not add a second with De Bruyne denied by a block on the line from Stefan Savic, but any lead is precious against an Atletico side who have made a speciality of frustrating Premier League giants in the past.

Liverpool found that out in 2020 when they lost both legs as holders in the last 16, while Manchester United were also eliminated at the same stage this season.

"We played an incredible top side who are difficult to face, but it is a good result," said Guardiola.

"We had chances to score a second and third. It is not easy to face a team with a lot of experience in this tournament. We will go there to score and try to win again."

Simeone marched off in defiant fashion at the final whistle and the Argentine will rightly feel Atletico are still in this tie - it would be folly to dismiss Simeone or his durable Champions League campaigners.

The onus though, is now on them to attack in the return leg.

"It is a bad result because we lost 1-0 and we were looking to win," Simeone said.

"It is clear we were playing against an extraordinary opponent. The numbers and statistics speak for themselves and they play in a very dynamic way. We had to suffer but we have to go to Madrid now and use the tools we have at our disposal.

"We need to be better but we are still in the tie. Let's see if we can have the ball more in the second leg and create more difficulties for our opponents but that comes with being calm and having the collective defensive effort."

However, alterations to Atletico's approach may well suit City more than having to break down the red and white wall of resistance that made their lives so difficult until that important De Bruyne strike on his 50th Champions League appearance for the club.