Midfielders Curtis Jones, Naby Keita and Alex Oxlade-Chamberlain are all sidelined too.

The Reds lost 4-1 at Napoli in the Group A opener, in what boss Jurgen Klopp called "the worst game we played since I was here" with Ajax beating Rangers 4-0 in the other game.

Ajax's only injury absentee is Netherlands left-back Owen Wijndal, who is out with an ankle problem.

The Dutch side have won all seven games in all competitions this season, with an aggregate score of 25-3.

"Ajax are in the Champions League and they belong there. Are they the strongest team in the competition? I haven't seen the rest yet," Klopp said.

"We have to show a reaction but that doesn't guarantee a result against Ajax. They've won all their games this season, they've had a massive rebuild but they're doing a really good job.

"We have not been consistent enough this season and we have to show that again. And that always starts with defending better."

The Reds have requested a minute's silence before kick-off against Ajax following the death of Queen Elizabeth II.