Draxler unleashed a right-foot shot into the bottom corner on 13 minutes.

Khedira nodded in the second four minutes later after Mats Hummels out-jumped the visitors' defence to head across goal to the Juventus midfielder.

Northern Ireland are third in the group on four points, with Germany top after winning their first three games.

Azerbaijan remain second in the table having retained their unbeaten record with a goalless draw against the Czech Republic.

Norway secured their first points of the qualifying campaign by defeating San Marino 4-1.
On the defensive

Northern Ireland manager Michael O'Neill's team selection reflected the change of emphasis from attack for Saturday's 4-0 win over San Marino to defence for the inevitable rearguard action against the four-time world champions.

Aaron Hughes came in to win his 104th cap and joined fellow experienced defenders Gareth McAuley and Jonny Evans in a back three, with Lee Hodson and Shane Ferguson deployed as wing-backs and the defensively-minded Corry Evans named in midfield.

Although the Germans predictably dominated territory and possession, Northern Ireland posed an attacking threat on the counter-attack.

Josh Magennis, preferred to Kyle Lafferty and Conor Washington in the lone striker role, was the visitors' stand-out player, working tirelessly throughout.

O'Neill's men were unable to convert a couple of breakaway chances in the first half, Jamie Ward's weak finish being easily gathered by Manuel Neuer and Magennis seeing his well-struck drive saved by the Germany goalkeeper.
All over in four minutes

Goalkeeper Michael McGovern was the hero when the sides last met at the Euro 2016 finals in Paris in June, making a number of outstanding saves to keep the final score down to 1-0.

The Norwich stopper was in action early on as he palmed away a Mario Gotze header, but poor defending in the early stages cost Northern Ireland dear as Draxler and Khedira found the net in that decisive four-minute spell.

Draxler shrugged off Gareth McAuley for the opening goal, while Khedira used his height advantage to climb above the Northern Ireland defence for the second.

The hosts had a number of chances to add to their tally in the second half but McGovern was rarely troubled, as Khedira in particular was guilty of profligacy in front of goal.

The facts you need to know

    Sami Khedira scored his first international goal in 1,099 minutes of action. Indeed, it was his first goal since the 7-1 win against Brazil at the 2014 World Cup.
    Northern Ireland conceded more than one goal in an international game for the first time since losing 2-0 in Romania in a European Championship qualifier in November 2014.
    The defeat is Northern Ireland's first in a qualifying game for almost two years, having previously gone eight unbeaten.
    Joachim Low won his 94th game as Germany coach, equalling Sepp Herberger's record.
    Northern Ireland goalkeeper Michael McGovern conceded more than one goal for the first time in the 18 internationals he has played.

What's next?

With the Germans strongly fancied to top the group, Northern Ireland's hopes of securing second place, and with it a shot at making Russia 2018 through the play-offs, will rest on less daunting fixtures than their visit to the formidable third-ranked team in the Fifa world standings.

The men in green host Azerbaijan in a potentially key match at Windsor Park on 11 November, with the Czech Republic entertaining Norway and San Marino at home to Germany on the same night.

What they said

Northern Ireland manager Michael O'Neill: "I was disappointed to go behind the way we did and to lose the second goal at that point in the game when we were trying to contain them.

"In the end if we had taken anything from here it would have been a huge bonus and whatever happens in the group, I don't see any of the other teams coming here and winning, so it's far from a disaster.

"We look forward to the game against Azerbaijan now and we have the incentive of going second in the group if we win that game."