The Argentine was two sets to one up on the world number 53 when play was suspended on Monday night.

He lost his serve early in the fourth set but fought back and served for the match at 5-4 only for Simon to save four match points.

But Del Potro went on to claim a 7-6 (7-1) 7-6 (7-5) 5-7 7-6 (7-5) victory.

The 29-year-old is in the quarter-finals for the first time since 2013 when he reached the last four before losing to Novak Djokovic in five sets.

Since then, he has struggled with a wrist injury that kept him out for two years.

Nadal, the world number one, reached his first Wimbledon quarter-final since 2011 with a straight-set win over unseeded Czech Jiri Vesely on Monday.