Hayford has replaced both strikers, Samira 'King Mira' Suleman and skipper Elizabeth Addo alias Ama Pele with youngster Grace Asantewaa and striker Jane Ayiyiem for the clash.
Suleman was deployed slightly ahead Addo in attack on Saturday and while the former struggled to get into the game, Ama Pele frustrated the home fans by holding onto the ball when she ould have passed to a teammate.
The oldest player in the team, 29-year-old Portia Boakye has been handed the captaincy for the day.
Replacements
Asantewaa, 17, plays her club football with Ampem Darkoa Ladies in Ghana and turns 18 on December 12, 2018.
Striker Ayiyiem has proven to be a consistent goalscorer for Ghana at all levels. The Police officer currently plays for Police Ladies in the Ghana National Women's League.
Black Queens Starting XI: Patricia Mantey (GK), Gladys Amfobea, Linda Eshun, Janet Egyir, Grace Asantewaa, Sherrifatu Sumaila, Juliet Acheampong, Priscilla Okyere, Faustina Ampah, Portia Boakye (14) and Jane Ayiyiem.