Henrikh Mkhitaryan and Jesse Lingard, who struggled in Saturday's derby defeat to Manchester City at Old Trafford, will also not travel to Holland.

The squad was announced on United's official website.

Mkhitaryan was selected for the derby despite suffering a thigh injury on international duty with Armenia and United manager Jose Mourinho is expected to address that issue in his news conference on Wednesday.

He was not at an open training session with the rest of the squad in Manchester earlier in the day.

United's regular starting full-backs, Antonio Valencia and Luke Shaw, have also both been left at home too -- paving the way for the likes of Matteo Darmian, Marcos Rojo and Tim Fosu-Mensah to stake a claim.