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British number two Kyle Edmund is out of the Brisbane International after losing to world number four Stan Wawrinka in the quarter-finals.
The world number 45 took the first set but lost 6-7 (2-7) 6-4 6-4 against the reigning US Open champion.
Edmund, 21, impressed but Wawrinka broke serve at 3-2 in the second set and twice in the decider to win in two hours 36 minutes.
The Swiss 31-year-old will play third seed Kei Nishikori in the semi-finals.
