With Bayern Munich, Chelsea, Juventus and Real Madrid all failing to win their respective groups, it means one of them could now be drawn against another top-tier club in Barcelona, Manchester City, Manchester United and Paris Saint-Germain.

The draw for the first knockout round will be made at 11 a.m. GMT / 6 a.m. ET on Monday, when group winners will be paired against group runners up. The group winners will be at home in the second leg.

Group winners: Barcelona, Besiktas, Liverpool, Manchester City, Manchester United, Paris Saint-Germain, Roma, Tottenham Hotspur.

Runners-up: Bayern Munich, Chelsea, FC Basel, FC Porto, Juventus, Real Madrid, Sevilla, Shakhtar Donetsk.

Teams from the same country cannot draw each other, nor can teams who played each other in the group stage.

The task is made especially hard for Chelsea. As the other four English sides won their groups, and Chelsea cannot be drawn against Roma again, it leaves only three possible opponents: Barcelona, Besiktas or Paris Saint-Germain -- meaning they have a very high chance of a tough tie.

Bayern Munich, Juventus and Real Madrid are also likely to face a big tie in the last-16, with Liverpool and both Manchester City and Manchester United on their shortlist of opposition.

Possible opponents for all round-of-16 teams

Barcelona: Bayern Munich, Chelsea, FC Basel, FC Porto, Shakhtar Donetsk.

Bayern Munich: Barcelona, Besiktas, Liverpool, Manchester City, Manchester United, Roma, Tottenham Hotspur.

Besiktas: Bayern Munich, Chelsea, FC Basel, Juventus, Real Madrid, Sevilla, Shakhtar Donetsk.

Chelsea: Barcelona, Besiktas, Paris Saint-Germain.

FC Basel: Barcelona, Besiktas, Liverpool, Manchester City, Paris Saint-Germain, Roma, Tottenham Hotspur.

Juventus: Besiktas, Manchester City, Liverpool, Manchester United, Paris Saint-Germain, Tottenham Hotspur.

Liverpool: Bayern Munich, FC Basel, FC Porto, Juventus, Real Madrid, Shakhtar Donetsk.

Manchester City: Bayern Munich, FC Basel, FC Porto, Juventus, Real Madrid, Sevilla.

Manchester United: Bayern Munich, FC Porto, Juventus, Real Madrid, Sevilla, Shakhtar Donetsk.

Paris Saint-Germain: Chelsea, FC Basel, FC Porto, Juventus, Real Madrid, Sevilla, Shakhtar Donetsk.

Real Madrid: Besiktas, Liverpool, Manchester City, Manchester United, Paris Saint-Germain, Roma.

Roma: Bayern Munich, FC Basel, FC Porto, Real Madrid, Sevilla, Shakhtar Donetsk.

Tottenham Hotspur: Bayern Munich, FC Basel, FC Porto, Juventus, Sevilla, Shakhtar Donetsk.

Sevilla: Besiktas, Manchester City, Manchester United, Paris Saint-Germain, Roma, Tottenham Hotspur.

Shakhtar Donetsk: Barcelona, Besiktas, Liverpool, Manchester United, Paris Saint-Germain, Roma, Tottenham Hotspur.

FC Porto: Barcelona, Liverpool, Manchester City, Manchester United, Paris Saint-Germain, Roma, Tottenham Hotspur.

The first legs will take place on Feb. 13, 14, 20 and 21. The second legs will then take place on March 6, 7, 13 and 14.