Unbeaten Ligue 1 leaders and holders Paris St-Germain suffered a shock French League Cup exit against the top-flight's bottom side Guingamp.
Having missed one earlier, Marcus Thuram - son of France legend Lilian - scored an injury-time penalty, adding to Yeni N'Gbakoto's earlier spot-kick for a 2-1 win.
Neymar netted for PSG, who have won the trophy in the last five seasons.
Thierry Henry's struggling Monaco side also progressed to the semi-finals.
Monaco, in 19th place in the table and five points off safety, went through courtesy of a marathon 8-7 penalty shootout victory over Rennes - which included 22 penalties - after the game finished 1-1.