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Atletico Madrid claimed a big victory over Juventus in the Champions League last 16 first leg thanks to two goals from their centre-backs at set-pieces.
Diego Simeone's side were denied a penalty and an Alvaro Morata goal by the video assistant referee before they opened the scoring.
Jose Maria Gimenez pounced from eight yards after Morata's header was blocked by Mario Mandzukic.
Diego Godin netted a half-volley, via a deflection off Cristiano Ronaldo.
Striker Costa and midfielder Thomas Partey of Atletico Madrid and Juve left-back Alex Sandro will all miss the second leg on Tuesday, 12 March after picking up their third bookings of the tournament.
Ronaldo - who is aiming to win a sixth Champions League and a fourth in a row - had Juve's best chance as his powerful 35-yard free-kick was tipped over by Jan Oblak.
Real Madrid are the only side to knock Atletico Madrid out of the Champions League knockout stages since Diego Simeone took over - four years in a row from 2014 to 2017
Atleti have not been at their best in La Liga this season but fully deserved a victory in a game involving the teams to lose four of the past five Champions League finals.
They were denied a first-half penalty, which was initially awarded when Mattia de Sciglio brought down Costa, who was making his first start since 2 December following injury. The referee overturned his decision after the VAR officials told him the offence had taken place outside the box.
Atleti stepped things up in the second half and Costa missed a glorious one-on-one chance before Antoine Griezmann had a lob brilliantly tipped on to the crossbar by Wojciech Szczesny.
They thought they had taken the lead when former Juve striker Morata headed home from Filipe Luis' cross but after watching the incident again on a pitchside screen, referee Felix Zwayer ruled the Chelsea loanee had shoved Giorgio Chiellini before getting the ball.
Their heads did not drop however and Morata, a second-half replacement for Costa, had a hand in the opener as his header was half-cleared by Mandzukic to Gimenez, who blasted home.
Five minutes later, it was another goal by another Uruguayan central defender. Another ricochet from Mandzukic found its way to Godin, who hit an acrobatic effort from a tight angle into the back of the net.
Nine of their starting line-up have played in a Champions League final for Atletico, with four playing in both 2014 and 2016. With more performances like this they could get a chance to go one better - this season's final on 1 June is to be played at their Wanda Metropolitano home.
Cristiano Ronaldo reminded Atleti fans of how many European Cups he has won (when the score was 0-0)
Ronaldo joined Juventus from Real Madrid in the summer for £99m hoping to win the Champions League with a third different club. He has won the past three with Real, and four in the past five years - as well as the 2008 trophy at Manchester United.
He was meant to be the final piece in the jigsaw for Juventus, who last won European club football's greatest trophy in 1995-96. But despite being the tournament's all-time top scorer - with 121 goals - and winning or sharing the Golden Boot for six consecutive seasons, he has not had quite the same impact in Europe for Juventus.
The 19-goal top scorer in Serie A has only netted once in his six European games for the club and was sent off on his debut in the tournament against Valencia.
The 34-year-old had seven shots against his old city rivals, but only one on target - a wonderful long-range free-kick well saved by Oblak.
And in three weeks' time at the Allianz Stadium, Juventus need him to put in one of his greatest Champions League performances if they are going to breach one of Europe's top defences - twice.
