Saturday's win over previously unbeaten Saracens took Rob Baxter's side three points clear at the summit.

Exeter have changed their entire front row from that game, while Ollie Devoto is in at centre and England's Henry Slade is fit enough to make the bench.

Saints' only change is Jamie Gibson replacing Tom Wood in the back row.

Wales fly-half Dan Biggar kicked 20 points in Northampton's victory at Worcester in their most recent outing.

Northampton: Tuala; Collins, Francis, Burrell, Naiyaravoro; Biggar, Reinach; Waller (co-capt), Hartley (co-capt), Hill, Ribbans, Lawes, Gibson, Ludlam, Harrison.

Replacements: Marshall, Van Wyk, Franks, Ratuniyaraw, Wood, Brussow, Mitchell, Dingwall.

Exeter: Simmonds; Cordero, Whitten, Devoto, O'Flaherty; Steenson (capt), Maunder; Moon, Taione, Williams, Lees, Skinner, Lonsdale, Armand, Kvesic.

Replacements: Cowan-Dickie, Hepburn, Francis, Hill, Lawday, White, Slade, Dollman.