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England seam bowler Pat Brown has withdrawn from the one-day and Twenty20 legs of the South Africa tour because of a stress fracture in his lower back.
Brown, 21, had a recurrence of symptoms while preparing to play for Melbourne Stars in Australia's Big Bash League, and scans showed a partial fracture.
He will not play for the rest of the winter and will return to Worcestershire to start rehabilitation.
England will announce a replacement in a due course.
The tourists face South Africa in three one-day internationals and three T20s in February.
Brown is yet to make his ODI debut for England but played four T20s in the series win over New Zealand in November.
